Evaluation of possible Acetaminophen toxicity; diagnose and monitor toxicity. Serum concentration and half-life are the only way to assess degree of toxicity in early stages - liver function studies (e.g., bilirubin, liver function enzymes) will not show clinically significant increases until after tissue damage has occurred and therapy would be ineffective.
To diagnose and monitor toxicity if an overdose has occurred and if an antidote is required. This test will help determine risk of liver damage and monitor the outcome of antidote treatment.
When it is suspected that a person has taken more than the recommended dose of acetaminophen (4g/ 24 hours in adults and 90 mg/kg/day in children) for an extended period to alleviate pain or fever.
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